Quick answer from a licensed plumber: They seal different things. Teflon (PTFE) tape and pipe dope seal threaded pipe joints (tape for most home jobs, dope for larger/metal or gas-rated work). Plumber’s putty seals under fixtures like sink drains and faucet bases. Silicone is a permanent waterproof caulk for seams and gaps. Using the wrong one is the #1 cause of leaks I get called to fix.

Which Sealant for Which Job

Product Use it for Don’t use on
Teflon tape Threaded pipe connections Compression fittings, drain bodies
Pipe dope Metal/large threaded joints, gas (rated type) Plastic threads it can attack
Plumber’s putty Under sink drains, faucet/strainer bases Plastic that cracks, pressure joints
Silicone Permanent waterproof seams, gaps Threaded pressure joints

Teflon Tape vs Pipe Dope

For threaded joints, Teflon tape (3–5 wraps, clockwise) handles nearly every household connection. Pipe dope is preferred on larger metal threads and is required in a gas-rated version for gas lines. Many pros use both on critical joints.

Plumber’s Putty vs Silicone

Plumber’s putty stays pliable and is perfect under a sink drain or faucet base because it’s removable for future service. Silicone sealant cures hard and permanent — great for a backsplash or shower seam, wrong for anything you’ll need to take apart.

The Plumber’s Verdict

Keep all four on the shelf — they’re cheap and each solves a different leak. Tape/dope for threads, putty for fixture bases, silicone for permanent waterproofing.

FAQ

Can I use Teflon tape instead of plumber’s putty?

No — they do different jobs. Tape seals threaded joints; putty seals under fixtures like sink drains. They’re not interchangeable.

Which way do I wrap Teflon tape?

Clockwise (the direction the fitting threads on), 3–5 wraps, so it tightens rather than unravels.

Is plumber’s putty or silicone better for a sink drain?

Plumber’s putty for most metal sink drains (removable later). Use silicone for some plastic fixtures or where the manufacturer specifies it.